MAP-DyS: An Interactive Framework for Mapping Analytic Decision Pathways in Subtyping Research

May 18, 2026·
Anna Yi Leung
Anna Yi Leung
Shared first-authorship
,
Daniel Kristanto
Shared first-authorship
,
Carsten Gießing
,
John PA Ioannidis
,
Andrea Hildebrandt
Shared senior-authorship
,
Xenia Schmalz
Shared senior-authorship
· 0 min read
Abstract
Subtyping approaches are widely used in psychological and cognitive research to classify individuals into subgroups based on shared behavioural or cognitive characteristics, particularly when addressing heterogeneity in developmental conditions such as developmental dyslexia. However, subtyping analyses involve numerous methodological decisions, including the choice of theoretical models, data preprocessing strategies, performance indices, and statistical techniques. Variability in these analytic decisions can lead to inconsistent subgroup identification and complicate comparisons across studies, yet such methodological variability is rarely systematically mapped. To support transparent examination of analytic decision pathways in subtyping research, we developed MAP-DyS, an open-source interactive Shiny app that enables researchers to explore and compare methodological choices across subtyping studies. To demonstrate the approach, we compiled a corpus of developmental dyslexia subtyping studies identified through a systematic search of four academic databases and extracted key analytic decision points reported in these studies. The resulting dataset illustrates substantial variability in theoretical models, preprocessing procedures, statistical methods, and reported subgroups. MAP-DyS allows users to interactively visualise these decision pathways and examine how different methodological configurations are represented across the literature. By making analytic variability transparent and navigable, the tool supports researchers in critically evaluating existing subtyping practices and designing more transparent and reproducible subtyping studies. Although demonstrated using developmental dyslexia research, the framework is designed to be adaptable to other areas of psychological and behavioural research that employ subtyping or classification approaches.
Type
Publication
medRxiv
publications
Anna Yi Leung
Authors
Research Scientist in Psycholinguistics and Metascience
I am a doctoral researcher in psycholinguistics at the Ludwig-Maximilians-University of Munich, formerly trained and served as a Chinese language teacher in Hong Kong primary and secondary schools. My research revolves around the cognitive mechanisms underlying reading development and the methodology used to identify subtypes of developmental dyslexia. I also build infrastructures based on metascientific principles to help synthesise research findings in psychological sciences. I am committed to bridging the gap between scientific research and the actual practice in the educational and clinical settings. My goal is to translate cross-disciplinary knowledge for researchers, educators, practitioners, and parents by connecting insights across fields.